The chemistry between Dr. Caitlin Lenox and Dr. Mitch Ripley has been electric this season.
We have an unlikely romance heating up on Chicago Med Season 11 as Dr. Caitlin Lenox (Sarah Ramos) continues to take a walk on the wild side with a jaw-dropping hook up with Dr. Mitch Ripley (Luke Mitchell).
Amid Lenox’s ongoing health crisis, the E.D. Chief has been embracing a new recklessness on Season 11, and Ripley has been picking up on the sudden 180. The pair got closer than ever during Season 11’s fall finale after Lenox and Ripley saved a domestic abuse victim and agreed to cover up a jaw-dropping murder after they were held hostage by the abusive husband. Ripley was left rattled by the traumatic incident, while Lenox instantly pretended nothing happened, leading to a gripping cat-and-mouse tension between the doctors after they reunited at Gaffney in the days following the traumatic event.
“The writers in the writers’ room and I got very excited about the possibilities of how [Ripley and Lenox] would get along,” Chicago Med showrunner Allen MacDonald said while chatting about the Ripley-Lenox pairing. “And how they would work together, and how they would kind of push each other to be better doctors.”
Mitch Ripley suspects Lenox is hiding something on Chicago Med
Med’s showrunner reveals that while Lenox has been keeping her cards close to her chest this season after testing positive for prion disease, Ripley suspects Lenox is silently struggling after the turbulent events of Season 11’s fall finale. Ripley has been left in the dark about the reason behind her recent impulsiveness, but he desperately wants to be illuminated as he finds himself processing the murder alone.
“After that event happens, Ripley’s going to be a little shaken up by it. He’s going to be thinking about it a lot. But Lenox is going to pretend like everything is back to normal and that it didn’t affect her at all,” MacDonald told NBC Insider.

Chicago Med Season 11
One Chicago Wednesdays are here!
Fresh off an extended fall hiatus, new Chicago Med episodes begin airing January 7, 2026 every Wednesday at 8/7c. New episodes are available to stream on Peacock Thursdays at 6 a.m. ET.
Keep up with your favorite doctors Sharon Goodwin (S. Epatha Merkerson), Daniel Charles (Oliver Platt), Dean Archer (Steven Weber), Hannah Asher (Jessy Schram), Mitch Ripley (Luke Mitchell), Caitlin Lenox (Sara Ramos), and John Frost (Darren Barnett) as they navigate the highs and lows of Gaffney Chicago Medical Center.
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Chihards watched Lenox embrace this frustratingly blasé attitude during Season 11’s “Frost on Fire” when she returned to work, and Ripley was left mystified by his co-conspirator’s lack of emotion. In fact, Ripley has been catching on to Lenox’s erratic behavior all season long, and it reached a breaking point as he finally confronted Lenox on her lack of reaction to the traumatic event.
“Ripley’s going to sense that there’s like this churning volcano of emotion in her that she is not dealing with. And we know as the audience members that that has to do with her prion disease diagnosis, but he doesn’t know that yet,” he explained. “Lenox has been spending the whole season with this secret… But I think [Ripley will] sense something is up with her, and he’s going to kind of push at that a little bit and challenge her in a way that she’s not used to.”
Lenox and Ripley hooked up after a heated argument
As Lenox made to leave work, Ripley intercepted her in the elevator lobby to ask her how her first day back. Instantly clocking the pending interrogation, an irritated Lenox decided to take the stairs instead. But Ripley wasn’t having it, following Lenox into the stairwell to ask her what her problem was and call her out for her emotionless response.
“You went through something really traumatic,” Ripley said, adding, “I mean, we both did.”
“I’ve served in combat zones; this was nothing,” Lenox reminded him as she continued up the stairs. As Ripley followed her with more questions, Lenox snapped. “What do you want? You want me to start crying? Tell you I can’t sleep? I’m having nightmares and keep flashing back to that night?”
“I can’t stop thinking about it,” Ripley admitted, but Lenox told him she’d moved on.
“I don’t buy it, you’re not a robot,” Ripley said, racing after Lenox and confessing that something had been off about her for a while. “You keep throwing yourself head first into these dangerous situations like you got a death wi-“
Lenox suddenly turned back, silencing Ripley with a passionate kiss. Ripley was taken aback, but after a heated beat, returned the kiss in kind. The conversation was subsequently snuffed as the Gaffney heartthrobs then hooked up in a Gaffney supply closet, a gripping twist to the emotional rollercoaster they’ve navigated this season.
Watch Chicago Med Wednesdays at 8/7c on NBC and the next day on Peacock.