Rena Sofer Exits General Hospital as Lois… For Now md13

Rena Sofer’s emotional farewell as Lois Cerullo left fans reaching for tissues — but GH confirms the fan favorite could still come home again.

Rena Sofer’s latest run as Lois Cerullo came to an emotional end during the October 24 episode of General Hospital. Lois shared a heartfelt farewell with her daughter Brook Lynn before leaving Port Charles once again. The exit marks the conclusion of Sofer’s 2023 return to the long-running ABC soap — though producers confirm this may not be goodbye forever, Soap Opera Digest reported.

Sofer’s Impact on GH

Sofer first joined General Hospital in 1993 as the vibrant and outspoken Lois Cerullo, a fan favorite who quickly became one half of a daytime super couple alongside Ned Ashton (Wally Kurth). Their chemistry and charm made them one of the defining pairs of the ’90s soap era. Sofer’s portrayal earned her a Daytime Emmy Award in 1995, solidifying her place in GH history.

After leaving in 1996 to start a family with Kurth, Sofer transitioned into primetime television with appearances on FriendsSeinfeldJust Shoot Me, and 24. She later returned to daytime as Quinn Fuller on The Bold and the Beautiful, where she spent nearly a decade until 2022.

A Return That Fans Welcomed

When Lois returned in 2023, it was a full-circle moment for GH viewers who had long hoped to see her again. Sofer’s comeback was originally slated as a limited run but was extended due to the overwhelmingly positive response. Her storyline placed Lois at the heart of one of the show’s most emotional plots — Brook Lynn’s (Amanda Setton) discovery that Lois had kept secrets about her teenage pregnancy and the son she’d given up.

A Goodbye with a Promise

In her final scenes, Lois revealed she was leaving for Seoul, South Korea, to serve as a tour manager for Blaze (Jacqueline Grace Lopez). Through tears, she assured Brook Lynn, “The second you need me, I will drop everything and come running.” It was a fitting exit for the loyal, big-hearted Lois — and one that left the door wide open for a future return.

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